Sex hormone-binding globulin has no effect on salivary testosterone
نویسندگان
چکیده
منابع مشابه
Investigation of Sex-Hormone Binding Globulin for Testosterone and Estradiol
The aim of this study was to find reasons for the interference of sex-hormone binding globulin (SHBG) in direct radloimmunoassays (RIAs) for testosterone and estradiol. 1251.. labeled testosterone and estradiol were compared with 3Hlabeled testosterone and estradiol for their affinity to SHBG. The 3H-Iabeled steroids bound far more avidly to SHBG than did the corresponding 1251-labeled steroids...
متن کاملEffect of anticonvulsants on plasma testosterone and sex hormone binding globulin levels.
Plasma sex hormone binding globulin (SHBG) and testosterone levels were measured in 29 patients with epilepsy (16 men and 13 women), most of them on chronic therapy with anticonvulsant drugs. Sex hormone binding globulin concentrations were increased in both sexes and testosterone levels in male patients. It is postulated that anticonvulsants may induce hepatic synthesis of SHBG.
متن کاملThe Evaluation of Serum Level of Testosterone and Sex Hormone- Binding Globulin in Men with Type 2 Diabetes
OBJECTIVE: To evaluate the relationship between serum level of testosterone and sex hormone-binding globulin in men with type 2 diabetes. MATERIALS AND METHODS: In this case-control study, forty men aged 40-70 with type 2 diabetes mellitus were randomly selected and compared with 40 non-diabetic men. The two groups were matched for their age and BMI. After complete observation and examination...
متن کاملCircadian variation in testosterone, sex hormone-binding globulin, and calculated non-sex hormone-binding globulin bound testosterone in healthy young and elderly men.
The circadian pattern in levels of serum total testosterone (T) in men becomes blunted with normal aging. However, because T not bound to sex hormone-binding globulin (non-SHBG-T) is felt to be a better representative of biologically available T than is total T, the possibility of a 24-h variation in non-SHBG-T in young men and the possibility that aging is associated with a blunting of that rh...
متن کاملEmpirical estimation of free testosterone from testosterone and sex hormone-binding globulin immunoassays.
BACKGROUND The growing interest in measuring blood free testosterone (FT) is constrained by the unsuitability of the laborious reference methods for wider adoption in routine diagnostic laboratories. Various alternative derived testosterone measures have been proposed to estimate FT from either additional assay steps or calculations using total testosterone (TT) and sex hormone-binding globulin...
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ژورنال
عنوان ژورنال: Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
سال: 2016
ISSN: 0004-5632,1758-1001
DOI: 10.1177/0004563216646800